1. Gene
  2. CHST9 - carbohydrate sulfotransferase 9 Gene

CHST9 - carbohydrate sulfotransferase 9 Gene

Homo sapiens

Also known as GalNAc4ST2; GALNAC4ST-2

Gene ID: 83539 | Gene type: protein coding

About CHST9

Cytogenetic location: 18q11.2 Genomic coordinates (GRCh38): 18:26,906,481-27,185,308 (from NCBI)

This gene has 3 transcripts (splice variants), 128 orthologues and 6 paralogues. Biased expression in spleen (RPKM 1.3), testis (RPKM 1.2) and 13 other tissues.

Summary

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is localized to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Sulfate groups on carbohydrates confer highly specific functions to glycoproteins, glycolipids, and proteoglycans, and are critical for cell-cell interaction, signal transduction, and embryonic development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Aug 2011]

CHST9 Products(3)

mRNA Protein Name
NM_001256316.2 NP_001243245.1 carbohydrate sulfotransferase 9 isoform 2
NM_001398493.1 NP_001385422.1 carbohydrate sulfotransferase 9 isoform 1
NM_031422.6 NP_113610.2 carbohydrate sulfotransferase 9 isoform 1

CHST9 Protein Structure

Sulfotransfer_2

Sulfotransfer_2: Sulfotransferase family (205 - 438)

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  • 443 a.a.
Protein Preferred Names Protein Names

carbohydrate sulfotransferase 9

GalNAc-4-sulfotransferase 2

Orthologs Information

Species Symbol Source ID
Macaca mulatta CHST9 VGNC VGNC:71059
Canis familiaris CHST9 VGNC VGNC:49746
Bos taurus CHST9 VGNC VGNC:27349
Mus musculus CHST9 MGD MGI:1918617
Felis catus CHST9 VGNC VGNC:60893
Rattus norvegicus CHST9 RGD RGD:1307302