PSMG3 - proteasome assembly chaperone 3 Gene

Also Known as PAC3; C7orf48

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84262

About PSMG3

Cytogenetic location: 7p22.3 Genomic coordinates (GRCh38): 7:1,567,332-1,570,032 (from NCBI)

This gene has 3 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in bone marrow (RPKM 8.7), skin (RPKM 6.6) and 25 other tissues.

Summary

Enables molecular adaptor activity. Involved in chaperone-mediated protein complex assembly. Predicted to be part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

PSMG3 Products (2)

mRNA Protein Name
NM_001134340.2 NP_001127812.1 proteasome assembly chaperone 3
NM_032302.4 NP_115678.1 proteasome assembly chaperone 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables molecular adaptor activity IMP
IMP: Inferred from mutant phenotype
17189198 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
17189198 GOA
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
17189198 GOA
Biological Process GO Annotation Evidence References Source
involved in chaperone-mediated protein complex assembly IMP
IMP: Inferred from mutant phenotype
17189198 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PSMG3 Protein Structure

PAC3

PAC3: Proteasome assembly chaperone 3 (34 - 121)

  • 0
  • 100
  • 122 a.a.
Protein Preferred Names Protein Names

proteasome assembly chaperone 3

  • PAC-3

Related Diseases

Diseases Alias
Robinow Syndrome, Autosomal Dominant 1

  • Autosomal Dominant Robinow Syndrome 1

  • DRS1

  • Robinow Dwarfism

  • Fetal Face Syndrome

  • Acral Dysostosis With Facial And Genital Abnormalities

  • Robinow, Autosomal Dominant Syndrome, Type 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11338 PSMG3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus PSMG3 VGNC VGNC:64416
Macaca mulatta PSMG3 VGNC VGNC:76301
Bos taurus PSMG3 VGNC VGNC:33480
Mus musculus PSMG3 MGD MGI:1913756
Rattus norvegicus PSMG3 RGD RGD:2319950
Canis familiaris PSMG3 VGNC VGNC:45123
Others PSMG3 NCBI