ABLIM2 - actin binding LIM protein family member 2 Gene

Homo sapiens

Gene ID: 84448 | Gene type: protein coding

About ABLIM2

Cytogenetic location: 4p16.1 Genomic coordinates (GRCh38): 4:7,965,327-8,158,813 (from NCBI)

This gene has 16 transcripts (splice variants), 201 orthologues and 3 paralogues. Broad expression in spleen (RPKM 7.8), brain (RPKM 4.6) and 16 other tissues.

Summary

Predicted to enable actin filament binding activity. Predicted to be involved in lamellipodium assembly. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in actin Cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]

ABLIM2 Products(8)

mRNA	Protein	Name
NM_001130083.2	NP_001123555.1	actin-binding LIM protein 2 isoform 1
NM_001130084.2	NP_001123556.1	actin-binding LIM protein 2 isoform 2
NM_001130085.2	NP_001123557.1	actin-binding LIM protein 2 isoform 3
NM_001130086.2	NP_001123558.1	actin-binding LIM protein 2 isoform 4
NM_001130087.2	NP_001123559.1	actin-binding LIM protein 2 isoform 5
NM_001130088.2	NP_001123560.1	actin-binding LIM protein 2 isoform 7
NM_001286688.2	NP_001273617.1	actin-binding LIM protein 2 isoform 8
NM_032432.5	NP_115808.3	actin-binding LIM protein 2 isoform 6

ABLIM2 Protein Structure

LIM

VHP

0
100
200
300
400
500
611 a.a.

Protein Preferred Names

Protein Names

actin-binding LIM protein 2

abLIM-2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00107	ABLIM2 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	ABLIM2	VGNC	VGNC:69474
Canis familiaris	ABLIM2	VGNC	VGNC:37479
Felis catus	ABLIM2	VGNC	VGNC:59490
Bos taurus	ABLIM2	VGNC	VGNC:25508
Mus musculus	ABLIM2	MGD	MGI:2385758
Rattus norvegicus	ABLIM2	RGD	RGD:1303094

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