Fmo3 - flavin containing dimethylaniline monoxygenase 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 84493

Summary

Enables N,N-dimethylaniline monooxygenase activity; NADP binding activity; and amino acid binding activity. Involved in xenobiotic metabolic process. Located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in hypertension; inherited metabolic disorder; and trimethylaminuria. Orthologous to human FMO3 (flavin containing dimethylaniline monoxygenase 3). [provided by Alliance of Genome Resources, Apr 2022]

Fmo3 Products (1)

mRNA Protein Name
NM_053433.2 NP_445885.2 dimethylaniline monooxygenase [N-oxide-forming] 3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables N,N-dimethylaniline monooxygenase activity IDA
IDA: Inferred from direct assay
17173378 RGD
enables NADP binding IPI
IPI: Inferred from physical interaction
17173378 RGD
enables amino acid binding IPI
IPI: Inferred from physical interaction
17173378 RGD
Biological Process GO Annotation Evidence References Source
involved in xenobiotic metabolic process IDA
IDA: Inferred from direct assay
17173378 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dimethylaniline monooxygenase [N-oxide-forming] 3

  • FMO 3

  • dimethylaniline oxidase 3

  • flavin containing monooxygenase 3

  • hepatic flavin-containing monooxygenase 3

  • trimethylamine monooxygenase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W009247 N-Desmethylolanzapine 99.68% Unkown
HY-P4439 H-Met-Val-OH 99.40% Unkown
HY-RS05007 FMO3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W009247S1 N-Desmethylolanzapine-d8 hydrochloride / Unkown
HY-RS22171 Fmo3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28693 Fmo3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fmo3 NCBI NCBI:2328