Kpna2 - karyopherin subunit alpha 2 Gene

Also Known as importin

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 85245

Summary

Predicted to enable several functions, including histone deacetylase binding activity; nuclear import signal receptor activity; and nuclear localization sequence binding activity. Involved in regulation of transcription by glucose. Predicted to be located in cytoplasmic stress granule and cytosol. Predicted to be active in glutamatergic synapse and nucleoplasm. Predicted to be extrinsic component of postsynaptic specialization membrane. Orthologous to human KPNA2 (karyopherin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]

Kpna2 Products (2)

mRNA Protein Name
NM_001270802.1 NP_001257731.1 importin subunit alpha-1
NM_053483.2 NP_445935.2 importin subunit alpha-1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in postsynapse to nucleus signaling pathway IDA
IDA: Inferred from direct assay
18303947 RGD
involved in regulation of transcription by glucose IDA
IDA: Inferred from direct assay
11988093 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

importin subunit alpha-1

  • importin subunit alpha-2

  • karyopherin (importin) alpha 2

  • karyopherin alpha 2

  • nuclear import protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS17914 Kpna2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07416 KPNA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24383 Kpna2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kpna2 NCBI NCBI:3838