2. Gene
  3. CDKL1 - cyclin dependent kinase like 1 Gene

CDKL1 - cyclin dependent kinase like 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as P42; KKIALRE

Gene ID: 8814 | Gene type: protein coding

About CDKL1

Cytogenetic location: 14q21.3 Genomic coordinates (GRCh38): 14:50,326,265-50,397,298 (from NCBI)

This gene has 11 transcripts (splice variants), 194 orthologues and 26 paralogues. Ubiquitous expression in kidney (RPKM 3.9), endometrium (RPKM 2.6) and 24 other tissues.

Summary

This gene product is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. [provided by RefSeq, Nov 2018]

CDKL1 Products(4)

mRNA Protein Name
NM_001282236.2 NP_001269165.1 cyclin-dependent kinase-like 1 isoform 2
NM_001367064.1 NP_001353993.1 cyclin-dependent kinase-like 1 isoform 3
NM_001367065.1 NP_001353994.1 cyclin-dependent kinase-like 1 isoform 3
NM_004196.7 NP_004187.3 cyclin-dependent kinase-like 1 isoform 1

CDKL1 Protein Structure

Pkinase

Pkinase: Protein kinase domain (5 - 288)

  • 0
  • 100
  • 200
  • 300
  • 358 a.a.
Protein Preferred Names Protein Names

cyclin-dependent kinase-like 1

cyclin-dependent kinase-like 1 (CDC2-related kinase)

Related Diseases

Diseases Alias
Gene Duplication Disease

Gene Duplication Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02405 CDKL1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus CDKL1 VGNC VGNC:27138
Felis catus CDKL1 VGNC VGNC:60708
Canis familiaris CDKL1 VGNC VGNC:39064
Mus musculus CDKL1 MGD MGI:1918341
Macaca mulatta CDKL1 VGNC VGNC:70986
Rattus norvegicus CDKL1 RGD RGD:1305080