CDKL1 - cyclin dependent kinase like 1 Gene
Also Known as P42; KKIALRE
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 8814
About CDKL1
Cytogenetic location: 14q21.3
Genomic coordinates (GRCh38): 14:50,326,265-50,397,298 (from NCBI)
This gene has 11 transcripts (splice variants), 194 orthologues and 26 paralogues. Ubiquitous expression in kidney (RPKM 3.9), endometrium (RPKM 2.6) and 24 other tissues.
Summary
This gene product is a member of a large family of CDC2-related serine/threonine protein kinases that accumulates primarily in the nucleus. [provided by RefSeq, Nov 2018]
CDKL1 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001282236.2 | NP_001269165.1 | cyclin-dependent kinase-like 1 isoform 2 |
| NM_001367064.1 | NP_001353993.1 | cyclin-dependent kinase-like 1 isoform 3 |
| NM_001367065.1 | NP_001353994.1 | cyclin-dependent kinase-like 1 isoform 3 |
| NM_004196.7 | NP_004187.3 | cyclin-dependent kinase-like 1 isoform 1 |
CDKL1 Protein Structure
Pkinase
Pkinase: Protein kinase domain (5 - 288)
- 0
- 100
- 200
- 300
- 358 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cyclin-dependent kinase-like 1 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Gene Duplication Disease |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS02405 | CDKL1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Bos taurus | CDKL1 | VGNC | VGNC:27138 |
| Felis catus | CDKL1 | VGNC | VGNC:60708 |
| Canis familiaris | CDKL1 | VGNC | VGNC:39064 |
| Mus musculus | CDKL1 | MGD | MGI:1918341 |
| Macaca mulatta | CDKL1 | VGNC | VGNC:70986 |
| Rattus norvegicus | CDKL1 | RGD | RGD:1305080 |
| Others | CDKL1 | NCBI |
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