LMLN - leishmanolysin like peptidase Gene
Also Known as INV; MSP; GP63; IX14; LMNL1
Species: Homo sapiens
About LMLN
This gene has 11 transcripts (splice variants) and 193 orthologues. Broad expression in testis (RPKM 8.5), thyroid (RPKM 4.0) and 25 other tissues.
Summary
This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
LMLN Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001136049.3 | NP_001129521.3 | leishmanolysin-like peptidase isoform 1 precursor |
| NM_033029.4 | NP_149018.3 | leishmanolysin-like peptidase isoform 2 precursor |
LMLN Protein Structure
Peptidase_M8: Leishmanolysin (81 - 411)
Peptidase_M8: Leishmanolysin (418 - 603)
- 0
- 200
- 400
- 600
- 655 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
leishmanolysin-like peptidase |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Leishmaniasis |
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| Cutaneous Leishmaniasis |
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| Visceral Leishmaniasis |
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| Mucocutaneous Leishmaniasis |
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| Splenic Disease |
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| Rapp-Hodgkin Syndrome |
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| Erysipeloid |
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| Trichomoniasis |
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| Parasitic Protozoa Infectious Disease |
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| Megaesophagus |
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| Arthrogryposis Multiplex Congenita 2, Neurogenic Type |
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| Sleeping Sickness |
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| Trypanosomiasis |
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Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Mus musculus | LMLN | MGD | MGI:2444736 |
| Bos taurus | LMLN | VGNC | VGNC:30928 |
| Canis familiaris | LMLN | VGNC | VGNC:42716 |
| Felis catus | LMLN | VGNC | VGNC:63251 |
| Macaca mulatta | LMLN | VGNC | VGNC:74296 |
| Rattus norvegicus | LMLN | RGD | RGD:1311465 |
| Others | LMLN | NCBI |