ABCC10 - ATP binding cassette subfamily C member 10 Gene

Homo sapiens

Also known as MRP7; SIMRP7; EST182763

Gene ID: 89845 | Gene type: protein coding

About ABCC10

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:43,427,541-43,451,994 (from NCBI)

This gene has 10 transcripts (splice variants), 480 orthologues and 11 paralogues. Ubiquitous expression in ovary (RPKM 3.1), spleen (RPKM 3.0) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2010]

ABCC10 Products(3)

mRNA	Protein	Name
NM_001198934.2	NP_001185863.1	ATP-binding cassette sub-family C member 10 isoform MRP7
NM_001350518.2	NP_001337447.1	ATP-binding cassette sub-family C member 10 isoform 3
NM_033450.3	NP_258261.2	ATP-binding cassette sub-family C member 10 isoform MRP7A

ABCC10 Protein Structure

ABC_membrane

ABC_tran

ABC_membrane

ABC_tran

0
300
600
900
1200
1492 a.a.

Protein Preferred Names

Protein Names

ATP-binding cassette sub-family C member 10

ATP-binding cassette, sub-family C (CFTR/MRP), member 10

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00058	ABCC10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	ABCC10	RGD	RGD:1306696
Bos taurus	ABCC10	VGNC	VGNC:25469
Canis familiaris	ABCC10	VGNC	VGNC:37437
Mus musculus	ABCC10	MGD	MGI:2386976
Felis catus	ABCC10	VGNC	VGNC:67653
Macaca mulatta	ABCC10	VGNC	VGNC:81005

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