2. Gene
  3. ANGPTL1 - angiopoietin like 1 Gene

ANGPTL1 - angiopoietin like 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as ANG3; ARP1; AngY; ANGPT3; UNQ162; dJ595C2.2

Gene ID: 9068 | Gene type: protein coding

About ANGPTL1

Cytogenetic location: 1q25.2 Genomic coordinates (GRCh38): 1:178,849,535-178,871,077 (from NCBI)

This gene has 3 transcripts (splice variants), 284 orthologues and 25 paralogues. Broad expression in ovary (RPKM 20.0), placenta (RPKM 16.0) and 21 other tissues.

Summary

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and Angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008]

ANGPTL1 Products(2)

mRNA Protein Name
NM_001376763.1 NP_001363692.1 angiopoietin-related protein 1 precursor
NM_004673.4 NP_004664.1 angiopoietin-related protein 1 precursor

ANGPTL1 Protein Structure

Fibrinogen_C

Fibrinogen_C: Fibrinogen beta and gamma chains, C-terminal globular domain (278 - 489)

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  • 491 a.a.
Protein Preferred Names Protein Names

angiopoietin-related protein 1

ANG-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00690 ANGPTL1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ANGPTL1 VGNC VGNC:25890
Canis familiaris ANGPTL1 VGNC VGNC:37857
Mus musculus ANGPTL1 MGD MGI:1919963
Felis catus ANGPTL1 VGNC VGNC:67562
Macaca mulatta ANGPTL1 VGNC VGNC:69813
Rattus norvegicus ANGPTL1 RGD RGD:1598128
Others ANGPTL1 NCBI