ESAM - endothelial cell adhesion molecule Gene

Homo sapiens

Also known as W117m

Gene ID: 90952 | Gene type: protein coding

About ESAM

Cytogenetic location: 11q24.2 Genomic coordinates (GRCh38): 11:124,753,126-124,762,290 (from NCBI)

This gene has 6 transcripts (splice variants), 292 orthologues and 14 paralogues. Broad expression in placenta (RPKM 71.1), thyroid (RPKM 67.5) and 21 other tissues.

Summary

Enables cell-cell adhesion mediator activity. Involved in several processes, including bicellular tight junction assembly; cell-cell adhesion; and regulation of actin Cytoskeleton organization. Located in cell-cell junction and plasma membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

ESAM Products(1)

mRNA	Protein	Name
NM_138961.3	NP_620411.2	endothelial cell-selective adhesion molecule precursor

ESAM Protein Structure

V-set

Ig_2

0
100
200
300
390 a.a.

Protein Preferred Names

Protein Names

endothelial cell-selective adhesion molecule

2310008D05Rik

Recombinant ESAM Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70889	ESAM Protein, Human (HEK293, His)	Q96AP7 (Q30-A247 )	≥95%

Related Diseases

Diseases

Alias

Aqueous Misdirection

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04520	ESAM Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	ESAM	VGNC	VGNC:53356
Macaca mulatta	ESAM	VGNC	VGNC:72290
Rattus norvegicus	ESAM	RGD	RGD:1303286
Felis catus	ESAM	VGNC	VGNC:102878
Mus musculus	ESAM	MGD	MGI:1916774
Bos taurus	ESAM	VGNC	VGNC:50042
Others	ESAM	NCBI