SLC16A4 - solute carrier family 16 member 4 Gene

Homo sapiens

Also known as MCT4; MCT5

Gene ID: 9122 | Gene type: protein coding

About SLC16A4

Cytogenetic location: 1p13.3 Genomic coordinates (GRCh38): 1:110,362,857-110,391,026 (from NCBI)

This gene has 10 transcripts (splice variants), 244 orthologues and 13 paralogues. Biased expression in kidney (RPKM 44.3), placenta (RPKM 12.3) and 10 other tissues.

Summary

Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in monocarboxylic acid transport. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC16A4 Products(6)

mRNA	Protein	Name
NM_001201546.2	NP_001188475.1	monocarboxylate transporter 5 isoform 2
NM_001201547.2	NP_001188476.1	monocarboxylate transporter 5 isoform 3
NM_001201548.2	NP_001188477.1	monocarboxylate transporter 5 isoform 4
NM_001201549.2	NP_001188478.1	monocarboxylate transporter 5 isoform 5
NM_001319220.2	NP_001306149.1	monocarboxylate transporter 5 isoform 6
NM_004696.3	NP_004687.1	monocarboxylate transporter 5 isoform 1

SLC16A4 Protein Structure

MFS_1

0
100
200
300
400
487 a.a.

Protein Preferred Names

Protein Names

monocarboxylate transporter 5

MCT 4

Related Diseases

Diseases

Alias

Pancreatic Cancer

Pancreatic Carcinoma	Carcinoma Of Pancreas
Familial Pancreatic Carcinoma	Pancreatic Neoplasm
Pancreatic Carcinoma, Familial	Malignant Neoplasm Of Pancreas
Pancreatic Acinar Carcinoma	Pancreatic Tumor
Familial Pancreatic Cancer	Neoplasm Of The Pancreas
Cancer Of The Pancreas	Pancreatic Carcinoma, Somatic
Pancreatic Cancer, Somatic	Ca Body Of Pancreas
Ca Head Of Pancreas	Ca Tail Of Pancreas
Malignant Neoplasm Of Body Of Pancreas	Malignant Neoplasm Of Head Of Pancreas
Malignant Neoplasm Of Tail Of Pancreas	Pancreas Neoplasm
Exocrine Cancer	Exocrine Pancreas Carcinoma
Hereditary Pancreatic Cancer	Hereditary Pancreatic Carcinoma
PNCA	Pancreatic Cancer, Susceptibility To
Carcinoma Of Head Of Pancreas	Pancreatic Neoplasms
Pancreatic Tumors	Cancer, Pancreatic
Cancer Of Pancreas	Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Pharynx Squamous Cell Carcinoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS13026	SLC16A4 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	SLC16A4	VGNC	VGNC:65211
Mus musculus	SLC16A4	MGD	MGI:2385183
Bos taurus	SLC16A4	VGNC	VGNC:34690
Rattus norvegicus	SLC16A4	RGD	RGD:1359655
Canis familiaris	SLC16A4	VGNC	VGNC:46243
Macaca mulatta	SLC16A4	VGNC	VGNC:77398

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