EBAG9 - estrogen receptor binding site associated antigen 9 Gene

Also Known as EB9; PDAF

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9166

About EBAG9

Cytogenetic location: 8q23.2 Genomic coordinates (GRCh38): 8:109,539,702-109,565,996 (from NCBI)

This gene has 13 transcripts (splice variants) and 227 orthologues. Ubiquitous expression in thyroid (RPKM 14.2), adrenal (RPKM 7.5) and 25 other tissues.

Summary

This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by Estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]

EBAG9 Products (3)

mRNA Protein Name
NM_001278938.2 NP_001265867.1 receptor-binding cancer antigen expressed on SiSo cells
NM_004215.5 NP_004206.1 receptor-binding cancer antigen expressed on SiSo cells
NM_198120.3 NP_936056.1 receptor-binding cancer antigen expressed on SiSo cells

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor-binding cancer antigen expressed on SiSo cells

  • cancer-associated surface antigen RCAS1

EBAG9 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
EBAG9 O00559 SLC35B4 Homo sapiens Q969S0
Validated Y2H
32296183
Intra
EBAG9 O00559 ORMDL1 Homo sapiens Q9P0S3
Validated Y2H
32296183
Intra
EBAG9 O00559 VAPA Homo sapiens Q9P0L0
Validated Y2H
32296183
Intra
EBAG9 O00559 CFHR5 Homo sapiens Q9BXR6
Validated Y2H
32296183
Intra
EBAG9 O00559 VAPB Homo sapiens O95292
Validated Y2H
32296183
Intra
EBAG9 O00559 STX2 Homo sapiens P32856-2
Validated Y2H
32296183
Intra
EBAG9 O00559 NRAC Homo sapiens Q8N912
Validated Y2H
32296183
Intra
EBAG9 O00559 SLC35A4 Homo sapiens Q96G79
Validated Y2H
32296183
Intra
EBAG9 O00559 TMEM107 Homo sapiens Q6UX40
Validated Y2H
32296183
Intra
EBAG9 O00559 SLC35A1 Homo sapiens P78382
Validated Y2H
32296183
Intra
EBAG9 O00559 OR10AG1 Homo sapiens Q8NH19
Validated Y2H
32296183
Intra
EBAG9 O00559 STX3 Homo sapiens Q13277
Validated Y2H
32296183
Intra
EBAG9 O00559 REEP6 Homo sapiens Q96HR9-2
Validated Y2H
32296183
Intra
EBAG9 O00559 TPRG1 Homo sapiens Q6ZUI0
Validated Y2H
32296183
Intra
EBAG9 O00559 CLEC4G Homo sapiens Q6UXB4
Validated Y2H
32296183
Intra
EBAG9 O00559 PRAF2 Homo sapiens O60831
Validated Y2H
32296183
Intra
EBAG9 O00559 ACSL5 Homo sapiens Q9ULC5
Validated Y2H
32296183
Intra
EBAG9 O00559 APOL2 Homo sapiens Q9BQE5
Validated Y2H
32296183
Intra
EBAG9 O00559 CLN6 Homo sapiens Q9NWW5
Validated Y2H
32296183
Intra
EBAG9 O00559 STX1A Homo sapiens Q16623
Validated Y2H
32296183
Intra
EBAG9 O00559 BNIP3 Homo sapiens Q12983
Validated Y2H
32296183
Intra
EBAG9 O00559 CIAO2A Homo sapiens Q9H5X1
Validated Y2H
32296183
Intra
EBAG9 O00559 TRAF3IP3 Homo sapiens Q9Y228
Validated Y2H
32296183
Intra
EBAG9 O00559 SLC30A2 Homo sapiens Q9BRI3
Validated Y2H
32296183
Intra
EBAG9 O00559 PEX16 Homo sapiens Q9Y5Y5
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant EBAG9 Proteins

Cat. No. Product Name Accession Purity
HY-P76881 EBAG9 Protein, Human (His) O00559-1 (R28-S213) ≥ 90%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Cervical Adenocarcinoma

  • Adenocarcinoma Cervix Uteri

  • Adenocarcinoma Of Cervix

  • Adenocarcinoma Of The Uterine Cervix

  • Adenocarcinoma Of The Cervix Uteri
Endometrial Cancer

  • Endometrial Carcinoma

  • Endometrial Neoplasm

  • Malignant Neoplasm Of Endometrium

  • Endometrioid Carcinoma

  • Endometrial Neoplasms

  • Carcinoma, Endometrioid

  • Endometrial Cancer, Familial

  • Endometrial Carcinoma, Somatic

  • Endometrial Cancer, Susceptibility To

  • Endometrial Ca

  • Malignant Endometrial Neoplasm

  • Neoplasm Of Endometrium

  • Primary Malignant Neoplasm Of Endometrium

  • Tumor Of Endometrium

  • Carcinoma Of The Endometrium

  • Endometrioid Carcinoma Of Female Reproductive System

  • ENDMC

  • Carcinoma Endometrioid

  • Endometrial Cancers

  • Cancer, Endometrial

  • Uterine Corpus Cancer
Gallbladder Cancer

  • Gallbladder Carcinoma

  • Gallbladder Neoplasm

  • Malignant Neoplasm Of Gallbladder

  • Malignant Tumour Of Gallbladder

  • Gallbladder Ca

  • Localized Malignant Gallbladder Neoplasm

  • Malignant Tumor Of The Gallbladder

  • Tumor Of The Gallbladder

  • Cancer Of The Gallbladder

  • Carcinoma Gallbladder

  • Carcinoma Of Gallbladder

  • Gallbladder Neoplasms

  • Malignant Neoplasm Of Gallbladder Localized

  • Cancer Of Gallbladder

  • Primary Malignant Neoplasm Of Gallbladder
Endometriosis

  • Endometriosis, Site Unspecified

  • Endometrial Ectopia
Large Intestine Adenocarcinoma

  • Adenocarcinoma Of Large Intestine
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Cervical Cancer

  • Cervical Cancer, Somatic

  • Neoplasm Of Uterine Cervix

  • Cervix Cancer

  • Uterine Cervical Neoplasm

  • Cervical Neoplasm

  • Cervix Uteri Cancer

  • Tumor Of The Cervix Uteri

  • CERCA

  • Uterine Cervical Cancer

  • Neoplasms Cervical

  • Uterine Cervical Neoplasms

  • Cervical Cancers

  • Cancer, Cervical, Somatic

  • Malignant Tumor Of Cervix

  • Cervix Carcinoma
Lymphadenitis

  • Acute Lymphadenitis

  • Chronic Lymphadenitis

  • Adenitis

  • Chronic Adenitis

  • Acute Adenitis

  • Inflammation Of Lymph Node

  • Adenitis Nos

  • Inflammation Of Gland

  • Lymphatic Gland Inflammation

  • Lymph Gland Inflammation

  • Polyadenitis

  • Chronic Adenitis Of Any Lymph Node Except Mesenteric

  • Chronic Lymphadenitis Except Mesenteric

  • Chronic Non-Specific Lymphadenitis
Pancreas Disease

  • Abnormality Of The Pancreas

  • Pancreatic Diseases
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04123 EBAG9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20914 Ebag9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27431 Ebag9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus EBAG9 RGD RGD:1307293
Felis catus EBAG9 VGNC VGNC:97406
Mus musculus EBAG9 MGD MGI:1859920
Bos taurus EBAG9 VGNC VGNC:97262
Canis familiaris EBAG9 VGNC VGNC:40174
Macaca mulatta EBAG9 VGNC VGNC:72029
Others EBAG9 NCBI