STK17A - serine/threonine kinase 17a Gene

Also Known as DRAK1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9263

About STK17A

Cytogenetic location: 7p13 Genomic coordinates (GRCh38): 7:43,583,108-43,627,379 (from NCBI)

This gene has 4 transcripts (splice variants), 187 orthologues and 1 paralogue. Broad expression in lymph node (RPKM 25.5), bone marrow (RPKM 15.3) and 24 other tissues.

Summary

This gene is a member of the DAP kinase-related apoptosis-inducing protein kinase family and encodes an autophosphorylated nuclear protein with a protein kinase domain. The protein has apoptosis-inducing activity. [provided by RefSeq, Jul 2008]

STK17A Products (1)

mRNA Protein Name
NM_004760.3 NP_004751.2 serine/threonine-protein kinase 17A

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ATP binding IDA
IDA: Inferred from direct assay
9786912 GOA
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
9786912 GOA
Biological Process GO Annotation Evidence References Source
involved in intracellular signal transduction IDA
IDA: Inferred from direct assay
9786912 GOA
involved in positive regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
21489989 GOA
involved in positive regulation of fibroblast apoptotic process IMP
IMP: Inferred from mutant phenotype
9786912 GOA
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
9786912 GOA
involved in regulation of reactive oxygen species metabolic process IMP
IMP: Inferred from mutant phenotype
21489989 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
9786912 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

STK17A Protein Structure

Pkinase

Pkinase: Protein kinase domain (64 - 321)

  • 0
  • 100
  • 200
  • 300
  • 414 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase 17A

  • DAP kinase-related apoptosis-inducing protein kinase 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-163626A STK17A/B-IN-1 hydrochloride Inhibitor / Unkown
HY-148062 RSS0680 Degrader 99.85% Unkown
HY-163626 STK17A/B-IN-1 Inhibitor / Unkown
HY-RS13924 STK17A Human Pre-designed siRNA Set A Pre-designed Set / Unkown