Immp2l - IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) Gene

Also Known as IMP2; Tg(HLA-A/H2-D)2Enge

Species: Mus musculus

Gene Type: protein coding

Gene ID: 93757

Summary

Enables peptidase activity. Acts upstream of or within several processes, including cerebellum vasculature development; gamete generation; and mitochondrion organization. Located in mitochondrion. Part of mitochondrial inner membrane peptidase complex. Orthologous to human IMMP2L (inner mitochondrial membrane peptidase subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

Immp2l Products (1)

mRNA	Protein	Name
NM_053122.5	NP_444352.2	mitochondrial inner membrane protease subunit 2

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables peptidase activity	IGI IGI: Inferred from genetic interaction	15814844	MGI
enables peptidase activity	IMP IMP: Inferred from mutant phenotype	18094351	MGI

Biological Process GO Annotation	Evidence	References	Source
acts upstream of or within DNA damage response	IMP IMP: Inferred from mutant phenotype	21824519	MGI
acts upstream of or within blood circulation	IMP IMP: Inferred from mutant phenotype	21824519	MGI
acts upstream of or within brain development	IMP IMP: Inferred from mutant phenotype	21824519	MGI
acts upstream of or within cerebellum vasculature development	IMP IMP: Inferred from mutant phenotype	21824519	MGI
acts upstream of or within mitochondrial respiratory chain complex assembly	IMP IMP: Inferred from mutant phenotype	21824519	MGI
acts upstream of or within ovarian follicle development	IMP IMP: Inferred from mutant phenotype	18094351	MGI
acts upstream of or within ovulation	IMP IMP: Inferred from mutant phenotype	18094351	MGI
acts upstream of or within protein processing involved in protein targeting to mitochondrion	IGI IGI: Inferred from genetic interaction	15814844	MGI
acts upstream of or within respiratory electron transport chain	IMP IMP: Inferred from mutant phenotype	21824519	MGI
acts upstream of or within spermatogenesis	IMP IMP: Inferred from mutant phenotype	18094351	MGI
acts upstream of or within superoxide metabolic process	IMP IMP: Inferred from mutant phenotype	21824519	MGI

Cellular Component GO Annotation	Evidence	References	Source
part of mitochondrial inner membrane peptidase complex	IGI IGI: Inferred from genetic interaction	15814844	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names	Protein Names
mitochondrial inner membrane protease subunit 2	AAD mice IMP2-like protein

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS28389	Immp2l Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS06791	IMMP2L Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21872	Immp2l Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Immp2l	NCBI	NCBI:83943