CPA5 - carboxypeptidase A5 Gene
Species: Homo sapiens
About CPA5
This gene has 11 transcripts (splice variants), 145 orthologues and 8 paralogues. Restricted expression toward testis (RPKM 7.8).
Summary
Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active Carboxypeptidase domain. Cleavage of the pro region activates the enzyme (Wei et al., 2002 [PubMed 11836249]).[supplied by OMIM, Mar 2008]
CPA5 Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001127441.2 | NP_001120913.1 | carboxypeptidase A5 isoform 1 precursor |
| NM_001127442.2 | NP_001120914.1 | carboxypeptidase A5 isoform 2 precursor |
| NM_001318223.2 | NP_001305152.1 | carboxypeptidase A5 isoform 1 precursor |
| NM_080385.5 | NP_525124.3 | carboxypeptidase A5 isoform 1 precursor |
CPA5 Protein Structure
Propep_M14: Carboxypeptidase activation peptide (43 - 118)
Peptidase_M14: Zinc carboxypeptidase (145 - 422)
- 0
- 100
- 200
- 300
- 400
- 436 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
carboxypeptidase A5 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Amebiasis |
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