Srd5a2 - steroid 5 alpha-reductase 2 Gene

Also Known as 5ART2; S5AR 2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94224

Summary

Enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Acts upstream of or within androgen biosynthetic process and male genitalia development. Predicted to be located in cell body fiber; cytoplasm; and neuronal cell body. Is expressed in genitourinary system. Human ortholog(s) of this gene implicated in hypospadias and prostate Cancer. Orthologous to human SRD5A2 (steroid 5 alpha-reductase 2). [provided by Alliance of Genome Resources, Apr 2022]

Srd5a2 Products (1)

mRNA Protein Name
NM_053188.3 NP_444418.1 3-oxo-5-alpha-steroid 4-dehydrogenase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity IMP
IMP: Inferred from mutant phenotype
11606430 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within androgen biosynthetic process IMP
IMP: Inferred from mutant phenotype
15249131 MGI
involved in androgen biosynthetic process IMP
IMP: Inferred from mutant phenotype
15249131 MGI
acts upstream of or within male genitalia development IMP
IMP: Inferred from mutant phenotype
11606430 MGI
acts upstream of or within steroid biosynthetic process IMP
IMP: Inferred from mutant phenotype
11606430 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

3-oxo-5-alpha-steroid 4-dehydrogenase 2

  • 5 alpha-SR2

  • SR type 2

  • steroid 5 alpha reductase type2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13755 SRD5A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21944 Srd5a2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28461 Srd5a2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srd5a2 NCBI NCBI:6716