FOXQ1 - forkhead box Q1 Gene

Also Known as HFH1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 94234

About FOXQ1

Cytogenetic location: 6p25.3 Genomic coordinates (GRCh38): 6:1,312,098-1,314,758 (from NCBI)

This gene has 1 transcript (splice variant), 204 orthologues and 42 paralogues.

Summary

FOXQ1 is a member of the FOX gene family, which is characterized by a conserved 110-amino acid DNA-binding motif called the forkhead or winged helix domain. FOX genes are involved in embryonic development, cell cycle regulation, tissue-specific gene expression, cell signaling, and tumorigenesis (Bieller et al., 2001 [PubMed 11747606]).[supplied by OMIM, May 2009]

FOXQ1 Products (1)

mRNA Protein Name
NM_033260.4 NP_150285.3 forkhead box protein Q1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FOXQ1 Protein Structure

Forkhead

Forkhead: Forkhead domain (119 - 215)

  • 0
  • 100
  • 200
  • 300
  • 403 a.a.
Protein Preferred Names Protein Names

forkhead box protein Q1

  • HFH-1

Related Diseases

Diseases Alias
Ectodermal Dysplasia 5, Hair/Nail Type

  • ECTD5

  • Ectodermal Dysplasia 5
Ectodermal Dysplasia 6, Hair/Nail Type

  • ECTD6

  • Ectodermal Dysplasia 6
Ectodermal Dysplasia 7, Hair/Nail Type

  • ECTD7

  • Ectodermal Dysplasia 7

  • Dysplasia, Ectodermal, Type 7, Hair/Nail
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-134601 KH-3 Inhibitor 98.20% Unkown
HY-RS05077 FOXQ1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20930 Foxq1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27447 Foxq1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus FOXQ1 RGD RGD:621572
Bos taurus FOXQ1 VGNC VGNC:106747
Mus musculus FOXQ1 MGD MGI:1298228
Macaca mulatta FOXQ1 VGNC VGNC:104379
Felis catus FOXQ1 VGNC VGNC:102424
Others FOXQ1 NCBI