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TRANK1 - tetratricopeptide repeat and ankyrin repeat containing 1 Gene

Also Known as LBA1

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 9881

About TRANK1

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:36,826,819-36,945,744 (from NCBI)

This gene has 7 transcripts (splice variants), 150 orthologues, 2 paralogues and is associated with 1 phenotype. Ubiquitous expression in endometrium (RPKM 7.0), lymph node (RPKM 6.9) and 24 other tissues.

Summary

Predicted to enable ATP binding activity. [provided by Alliance of Genome Resources, Apr 2022]

TRANK1 Products (2)

mRNA	Protein	Name
NM_001329998.2	NP_001316927.1	TPR and ankyrin repeat-containing protein 1 isoform 1
NM_014831.3	NP_055646.2	TPR and ankyrin repeat-containing protein 1 isoform 2

TRANK1 Protein Structure

UvrD-helicase

UvrD_C

0
500
1000
1500
2000
2500
2925 a.a.

Protein Preferred Names	Protein Names
TPR and ankyrin repeat-containing protein 1	lupus brain antigen 1 homolog

Related Diseases

Diseases	Alias
Kleine-Levin Hibernation Syndrome	Kleine-Levin Syndrome Familial Kleine-Levin Syndrome Kleine Levin Syndrome Familial Hibernation Syndrome Recurrent Hypersomnolence Hypersomnia-Bulimia Syndrome
Recurrent Hypersomnia	Primary Recurrent Hypersomnia Hypersomnia Recurrent Disorders Of Excessive Somnolence Hypersomnia, Recurrent
Kohlschutter-Tonz Syndrome	Amelocerebrohypohidrotic Syndrome KTZS Epilepsy And Yellow Teeth Kohlschutter Tonz Syndrome Kohlschutter Syndrome Epilepsy Dementia Amelogenesis Imperfecta Epilepsy-Dementia-Amelogenesis Imperfecta Syndrome Epilepsy, Dementia, And Amelogenesis Imperfecta Kohlschutter'S Syndrome Kohlschütter-Tönz Syndrome Kohlschuetter-Toenz Syndrome Presenile Dementia Dementia
Bipolar Disorder	Bipolar Depression Manic Disorder Depression, Bipolar Bipolar Disorder Manic Phase Depressive-Manic Psych. Manic Bipolar Affective Disorder Manic Bipolar I Disorder Manic Depression Manic Depressive Disorder Mixed Bipolar Disorder Bipolar Affective Disorder Bipolar Affective Psychosis Bipolar Spectrum Disorder Manic Depressive Illness Depression Bipolar Bipolar Disorder, Mixed Major Affective Disorder Major Affective Disorder 1 Major Affective Disorder 2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14983	TRANK1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	TRANK1	VGNC	VGNC:82709
Felis catus	TRANK1	VGNC	VGNC:82406
Bos taurus	TRANK1	VGNC	VGNC:36282
Mus musculus	TRANK1	MGD	MGI:1341834
Rattus norvegicus	TRANK1	RGD	RGD:1563130
Canis familiaris	TRANK1	VGNC	VGNC:47775
Others	TRANK1	NCBI