2. Gene
  3. Hrh3 - histamine receptor H3 Gene

Hrh3 - histamine receptor H3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as H3R; Eae8; HH3R

Gene ID: 99296 | Gene type: protein coding

About Hrh3

Chromosome 2: 179,741,258-179,746,281 reverse strand.GRCm39:CM000995.3

This gene has 8 transcripts (splice variants), 117 orthologues, 32 paralogues and is associated with 26 phenotypes. Biased expression in frontal lobe adult (RPKM 17.2), cortex adult (RPKM 16.) and 8 other tissues.

Summary

Predicted to enable G protein-coupled amine receptor activity; amine binding activity; and heterocyclic compound binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; learning or memory; and regulation of secretion. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in myelin sheath; neuron projection; and plasma membrane. Predicted to be active in dendrite and synapse. Predicted to be integral component of plasma membrane. Is expressed in brain. Orthologous to human HRH3 (Histamine Receptor H3). [provided by Alliance of Genome Resources, Apr 2022]

Hrh3 Products(9)

mRNA Protein Name
NM_001409452.1 NP_001396381.1 histamine H3 receptor isoform 3
NM_001409453.1 NP_001396382.1 histamine H3 receptor isoform 4
NM_001409454.1 NP_001396383.1 histamine H3 receptor isoform 5
NM_001409456.1 NP_001396385.1 histamine H3 receptor isoform 2 precursor
NM_133849.4 NP_598610.1 histamine H3 receptor isoform 1
NM_001409457.1 NP_001396386.1 histamine H3 receptor isoform 2 precursor
NM_001409451.1 NP_001396380.1 histamine H3 receptor isoform 2 precursor
NM_001409458.1 NP_001396387.1 histamine H3 receptor isoform 2 precursor
NM_001409455.1 NP_001396384.1 histamine H3 receptor isoform 6

Hrh3 Protein Structure

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (47 - 422)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (68 - 95)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (106 - 136)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (151 - 169)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (194 - 224)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (350 - 380)

7tmA_Histamine_H3R

7tmA_Histamine_H3R: cd15296 (390 - 415)

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  • 445 a.a.
Protein Preferred Names Protein Names

histamine H3 receptor

experimental allergic encephalomyelitis susceptibility 8

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06365 HRH3 Human Pre-designed siRNA Set A / Unkown
HY-RS06366 Hrh3 Mouse Pre-designed siRNA Set A / Unkown
HY-RS06367 Hrh3 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Hrh3 NCBI NCBI:11255