Hrh3 - histamine receptor H3 Gene
Also Known as H3R; Eae8; HH3R
Species: Mus musculus
About Hrh3
This gene has 8 transcripts (splice variants), 117 orthologues, 32 paralogues and is associated with 26 phenotypes. Biased expression in frontal lobe adult (RPKM 17.2), cortex adult (RPKM 16.) and 8 other tissues.
Summary
Predicted to enable G protein-coupled amine receptor activity; amine binding activity; and heterocyclic compound binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; learning or memory; and regulation of secretion. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in myelin sheath; neuron projection; and plasma membrane. Predicted to be active in dendrite and synapse. Predicted to be integral component of plasma membrane. Is expressed in brain. Orthologous to human HRH3 (Histamine Receptor H3). [provided by Alliance of Genome Resources, Apr 2022]
Hrh3 Products (9)
| mRNA | Protein | Name |
|---|---|---|
| NM_001409452.1 | NP_001396381.1 | histamine H3 receptor isoform 3 |
| NM_001409453.1 | NP_001396382.1 | histamine H3 receptor isoform 4 |
| NM_001409454.1 | NP_001396383.1 | histamine H3 receptor isoform 5 |
| NM_001409456.1 | NP_001396385.1 | histamine H3 receptor isoform 2 precursor |
| NM_133849.4 | NP_598610.1 | histamine H3 receptor isoform 1 |
| NM_001409457.1 | NP_001396386.1 | histamine H3 receptor isoform 2 precursor |
| NM_001409451.1 | NP_001396380.1 | histamine H3 receptor isoform 2 precursor |
| NM_001409458.1 | NP_001396387.1 | histamine H3 receptor isoform 2 precursor |
| NM_001409455.1 | NP_001396384.1 | histamine H3 receptor isoform 6 |
Hrh3 Protein Structure
7tmA_Histamine_H3R: cd15296 (47 - 422)
7tmA_Histamine_H3R: cd15296 (68 - 95)
7tmA_Histamine_H3R: cd15296 (106 - 136)
7tmA_Histamine_H3R: cd15296 (151 - 169)
7tmA_Histamine_H3R: cd15296 (194 - 224)
7tmA_Histamine_H3R: cd15296 (350 - 380)
7tmA_Histamine_H3R: cd15296 (390 - 415)
- 0
- 100
- 200
- 300
- 400
- 445 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
histamine H3 receptor |
|