HS3ST2 - heparan sulfate-glucosamine 3-sulfotransferase 2 Gene

Also Known as 30ST2; 3OST2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9956

About HS3ST2

Cytogenetic location: 16p12.2 Genomic coordinates (GRCh38): 16:22,814,162-22,916,338 (from NCBI)

This gene has 2 transcripts (splice variants), 217 orthologues and 10 paralogues. Biased expression in brain (RPKM 12.4) and lung (RPKM 0.7).

Summary

Heparan sulfate biosynthetic Enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. This gene is expressed predominantly in brain and may play a role in the nervous system. [provided by RefSeq, Jul 2008]

HS3ST2 Products (1)

mRNA Protein Name
NM_006043.2 NP_006034.1 heparan sulfate glucosamine 3-O-sulfotransferase 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity IDA
IDA: Inferred from direct assay
9988768 GOA
Biological Process GO Annotation Evidence References Source
involved in glycosaminoglycan biosynthetic process IDA
IDA: Inferred from direct assay
9988768 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HS3ST2 Protein Structure

Sulfotransfer_1

Sulfotransfer_1: Sulfotransferase domain (115 - 350)

  • 0
  • 100
  • 200
  • 300
  • 367 a.a.
Protein Preferred Names Protein Names

heparan sulfate glucosamine 3-O-sulfotransferase 2

  • 3-OST-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06378 HS3ST2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus HS3ST2 VGNC VGNC:29959
Rattus norvegicus HS3ST2 RGD RGD:727787
Canis familiaris HS3ST2 VGNC VGNC:41792
Mus musculus HS3ST2 MGD MGI:1333802
Others HS3ST2 NCBI