2. Gene
  3. CDC34 - cell division cycle 34, ubiqiutin conjugating enzyme Gene

CDC34 - cell division cycle 34, ubiqiutin conjugating enzyme Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as UBC3; UBCH3; UBE2R1; E2-CDC34

Gene ID: 997 | Gene type: protein coding

About CDC34

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:531,760-542,087 (from NCBI)

This gene has 7 transcripts (splice variants), 126 orthologues and 24 paralogues. Ubiquitous expression in testis (RPKM 23.4), placenta (RPKM 14.2) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the ubiquitin-conjugating Enzyme family. Ubiquitin-conjugating Enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. [provided by RefSeq, Jul 2008]

CDC34 Products(1)

mRNA Protein Name
NM_004359.2 NP_004350.1 ubiquitin-conjugating enzyme E2 R1

CDC34 Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (14 - 154)

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  • 200
  • 236 a.a.
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 R1

(E3-independent) E2 ubiquitin-conjugating enzyme R1

Recombinant CDC34 Proteins

Cat. No. Product Name Accession Purity
HY-P79448 UBE2R1/CDC34 Protein, Human (Sf9, His, Strep) P49427 (A2-S236) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15301 CC0651 Inhibitor 99.03% Unkown
HY-RS02296 CDC34 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CDC34 VGNC VGNC:60654
Mus musculus CDC34 MGD MGI:102657
Bos taurus CDC34 VGNC VGNC:27066
Rattus norvegicus CDC34 RGD RGD:1305411
Canis familiaris CDC34 VGNC VGNC:38993
Macaca mulatta CDC34 VGNC VGNC:108493
Others CDC34 NCBI