HEPES hemisodium salt, 99%(T)
Based on 11 publication(s) in Google Scholar
HEPES hemisodium salt, 99%(T) is used as a buffer.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 103404-87-1
- Formula: C8H18N2O4S.1/2Na
- Molecular Weight:249.80
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) HEPES hemisodium salt, 99%(T)
More- Cancer Res. 2026 Feb 9. [Abstract]
- J Adv Res. 2025 Jul:73:265-282. [Abstract]
- Neuron. 2025 Jul 29:S0896-6273(25)00509-4. [Abstract]
- Chin Med. 2025 Jun 16;20(1):89. [Abstract]
- Biochem Pharmacol. 2026 Jul:249:117925. [Abstract]
- Int Immunopharmacol. 2023 Jul:120:110292. [Abstract]
- Int Immunopharmacol. 2022 Sep:110:108953. [Abstract]
- Bioorg Chem. 2026 Jun 19:180:110125. [Abstract]
- Structure. 2024 Dec 5;32(12):2287-2300.e4. [Abstract]
- Andrology. 2025 Feb;13(2):371-381. [Abstract]
- SSRN. 2026 May 6.
Biological Activity
Chemical Information
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CAS No. 103404-87-1
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Appearance Solid
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Molecular Weight 249.80
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Formula C8H18N2O4S.1/2Na
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Color White to off-white
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SMILES
O=S(O)(CCN1CCN(CC1)CCO)=O.[Na].[0.5]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (11)
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Journal Impact Factor
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Most Recent
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Cancer Res
The Farnesyl Transferase Inhibitor Darlifarnib (KO-2806) Resensitizes Relapsing Tumors to RAS Inhibition. [Abstract]2026 Feb 9. PMID: 41661652 -
J Adv Res
Matrix stiffness-dependent PD-L2 deficiency improves SMYD3/xCT-mediated ferroptosis and the efficacy of anti-PD-1 in HCC. [Abstract]2025 Jul:73:265-282. PMID: 39159723 -
Neuron
Social interaction in mice suppresses breast cancer progression via a corticoamygdala neural circuit. [Abstract]2025 Jul 29:S0896-6273(25)00509-4. PMID: 40752486 -
Chin Med
Quercetagetin alleviates liver fibrosis in non-alcoholic fatty liver disease by promoting ferroptosis of hepatic stellate cells through GPX4 ubiquitination. [Abstract]2025 Jun 16;20(1):89. PMID: 40524220 -
Biochem Pharmacol
Recruitment of tumor-associated macrophages via the CCL4-CCR5 axis promotes immune escape through PD-1 signaling in lung adenocarcinoma. [Abstract]2026 Jul:249:117925. PMID: 41876018 -
Int Immunopharmacol
2023 Jul:120:110292. PMID: 37182452 -
Int Immunopharmacol
Neobavaisoflavone inhibits allergic inflammatory responses by suppressing mast cell activation. [Abstract]2022 Sep:110:108953. PMID: 35724607 -
Bioorg Chem
Accelerated development of 4-HPPD inhibitors using a hybrid deep learning approach with Bayesian-guided reinforcement learning. [Abstract]2026 Jun 19:180:110125. PMID: 42348944 -
Structure
2024 Dec 5;32(12):2287-2300.e4. PMID: 39426373 -
Andrology
Cellular mechanism underlying leptin-induced anion secretion of rat epididymal epithelial cells. [Abstract]2025 Feb;13(2):371-381. PMID: 38778669 -
Solvent & Solubility
H2O : 116.67 mg/mL (467.05 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (245 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.0032 mL | 20.0160 mL | 40.0320 mL | 100.0801 mL |
| 5 mM | 0.8006 mL | 4.0032 mL | 8.0064 mL | 20.0160 mL | |
| 10 mM | 0.4003 mL | 2.0016 mL | 4.0032 mL | 10.0080 mL | |
| 15 mM | 0.2669 mL | 1.3344 mL | 2.6688 mL | 6.6720 mL | |
| 20 mM | 0.2002 mL | 1.0008 mL | 2.0016 mL | 5.0040 mL | |
| 25 mM | 0.1601 mL | 0.8006 mL | 1.6013 mL | 4.0032 mL | |
| 30 mM | 0.1334 mL | 0.6672 mL | 1.3344 mL | 3.3360 mL | |
| 40 mM | 0.1001 mL | 0.5004 mL | 1.0008 mL | 2.5020 mL | |
| 50 mM | 0.0801 mL | 0.4003 mL | 0.8006 mL | 2.0016 mL | |
| 60 mM | 0.0667 mL | 0.3336 mL | 0.6672 mL | 1.6680 mL | |
| 80 mM | 0.0500 mL | 0.2502 mL | 0.5004 mL | 1.2510 mL | |
| 100 mM | 0.0400 mL | 0.2002 mL | 0.4003 mL | 1.0008 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.