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  4. TAPS

TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH).

For research use only. We do not sell to patients.

TAPS Chemical Structure

TAPS Chemical Structure

CAS No. : 29915-38-6

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Based on 1 publication(s) in Google Scholar

Other Forms of TAPS:

TAPS Related Antibodies

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  • Purity & Documentation

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Description

TAPS is a biological buffer, remain lysozyme native structure intact and prevents thermal denaturation against high temperatures. TAPS exhibits pKa value of 8.1, while the half-maximum values of connexin channel activity is 8.5 (pH)[1][2].

Clinical Trial
Molecular Weight

243.28

Formula

C7H17NO6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=S(CCCNC(CO)(CO)CO)(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (513.81 mM; Need ultrasonic)

DMSO : 100 mg/mL (411.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1105 mL 20.5525 mL 41.1049 mL
5 mM 0.8221 mL 4.1105 mL 8.2210 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (247 KB) HNMR (244 KB) MS (80 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.1105 mL 20.5524 mL 41.1049 mL 102.7622 mL
5 mM 0.8221 mL 4.1105 mL 8.2210 mL 20.5524 mL
10 mM 0.4110 mL 2.0552 mL 4.1105 mL 10.2762 mL
15 mM 0.2740 mL 1.3702 mL 2.7403 mL 6.8508 mL
20 mM 0.2055 mL 1.0276 mL 2.0552 mL 5.1381 mL
25 mM 0.1644 mL 0.8221 mL 1.6442 mL 4.1105 mL
30 mM 0.1370 mL 0.6851 mL 1.3702 mL 3.4254 mL
40 mM 0.1028 mL 0.5138 mL 1.0276 mL 2.5691 mL
50 mM 0.0822 mL 0.4110 mL 0.8221 mL 2.0552 mL
60 mM 0.0685 mL 0.3425 mL 0.6851 mL 1.7127 mL
80 mM 0.0514 mL 0.2569 mL 0.5138 mL 1.2845 mL
100 mM 0.0411 mL 0.2055 mL 0.4110 mL 1.0276 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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TAPS Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TAPS29915-38-6Biochemical Assay Reagentshalf-maximumconnexinchannel activitylysozymethermal denaturationbiological bufferstabilityInhibitorinhibitorinhibit

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