HIV-1 inhibitor-26
HIV-1 inhibitor-26 (compound 9a) is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 value of 1.4 μM. HIV-1 inhibitor-26 has low cytotoxicity with a CC50 of 1486 μM in PBMCs. HIV-1 inhibitor-26 can be used for researching AIDS.
For research use only. We do not sell to patients.
- CAS No.: 2415504-88-8
- Formula: C43H33ClN2O9
- Molecular Weight:757.18
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 1.4 μM (HIV-1 RT)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | CC50 |
1486 μM
Compound: 9a
|
Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by XTT assay
Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by XTT assay
|
[PMID: 32244098] |
Chemical Information
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CAS No. 2415504-88-8
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Molecular Weight 757.18
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Formula C43H33ClN2O9
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SMILES
O=C(C1=CC=CC=C1)O[C@H]2[C@@](N3C4=CC=CC=C4C(C(C(NCC5=CC=C(C=C5)Cl)=O)=C3)=O)([H])O[C@@H]([C@H]2OC(C6=CC=CC=C6)=O)COC(C7=CC=CC=C7)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)