2415504-88-8
Chemical Structure
HIV-1 inhibitor-26
- CAS No.: 2415504-88-8
- Formula:C43H33ClN2O9
- Molecular Weight:757.18
IUPAC Name: (2R,3R,4R,5R)-2-((benzoyloxy)methyl)-5-(3-((4-chlorobenzyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)tetrahydrofuran-3,4-diyl dibenzoate
InChIKey: NYBPTUXEDGKBBP-PKGPUZNISA-N
SMILES: O=C(C1=CC=CC=C1)O[C@H]2[C@@](N3C4=CC=CC=C4C(C(C(NCC5=CC=C(C=C5)Cl)=O)=C3)=O)([H])O[C@@H]([C@H]2OC(C6=CC=CC=C6)=O)COC(C7=CC=CC=C7)=O
Biological Activity: HIV-1 inhibitor-26 (compound 9a) is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 value of 1.4 μM. HIV-1 inhibitor-26 has low cytotoxicity with a CC50 of 1486 μM in PBMCs. HIV-1 inhibitor-26 can be used for researching AIDS[1].
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HIV-1 inhibitor-26 | HIV-1 inhibitor-26 (compound 9a) is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 value of 1.4 μM. HIV-1 inhibitor-26 has low cytotoxicity with a CC50 of 1486 μM in PBMCs. HIV-1 inhibitor-26 can be used for researching AIDS. | |||||||||||||||||||||
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