(±)Homoeriodictyol
(±) Homoeriodictyol is a Aromatase/CYP19 inhibitor that can be used in breast cancer research.
For research use only. We do not sell to patients.
- CAS No.: 69097-98-9
- Formula: C16H14O6
- Molecular Weight:302.28
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Aromatase |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | Inhibition |
-0.537 %
Compound: DDD01025624
|
Toxicity liver stage against HepG2, at 10uM
Toxicity liver stage against HepG2, at 10uM
|
[PMID: 32078764] |
| HepG2 | Inhibition |
15.02 %
Compound: DDD01025624
|
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 2uM
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 2uM
|
[PMID: 32078764] |
| HepG2 | Inhibition |
-17.1 %
Compound: DDD01025624
|
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 10uM
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 10uM
|
[PMID: 32078764] |
(±) Homoeriodictyol (compound 5) (316.2-640×103 nM; 20 min (37 °C)) inhibits aromatase/CYP19 activity in human placental microsomes, with an IC50 of 25 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 69097-98-9
-
Molecular Weight 302.28
-
Formula C16H14O6
-
SMILES
O=C1C2=C(OC(C1)C3=CC=C(C(OC)=C3)O)C=C(O)C=C2O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)