2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. (±)Homoeriodictyol

(±) Homoeriodictyol is a Aromatase/CYP19 inhibitor that can be used in breast cancer research.

For research use only. We do not sell to patients.

(±)Homoeriodictyol

(±)Homoeriodictyol Chemical Structure

CAS No. : 69097-98-9

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(±)Homoeriodictyol Related Antibodies

Top Publications Citing Use of Products

View All Cytochrome P450 Isoform Specific Products:

View All Isoforms
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP1A2 CYP2D6 CYP2C9 CYP2C19 CYP3A CYP3A4 CYP17A1

  • Biological Activity

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Description

(±) Homoeriodictyol is a Aromatase/CYP19 inhibitor that can be used in breast cancer research[1].

IC50 & Target

Aromatase

 

Cellular Effect
Cell Line Type Value Description References
HepG2 Inhibition
-0.537 %
Compound: DDD01025624
Toxicity liver stage against HepG2, at 10uM
Toxicity liver stage against HepG2, at 10uM
[PMID: 32078764]
HepG2 Inhibition
15.02 %
Compound: DDD01025624
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 2uM
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 2uM
[PMID: 32078764]
HepG2 Inhibition
-17.1 %
Compound: DDD01025624
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 10uM
Screen against P. berghei liver stage (PbLuc), transformed with Luciferase, at 10uM
[PMID: 32078764]
In Vitro

(±) Homoeriodictyol (compound 5) (316.2-640×103 nM; 20 min (37 °C)) inhibits aromatase/CYP19 activity in human placental microsomes, with an IC50 of 25 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(±)Homoeriodictyol Related Antibodies
Molecular Weight

302.28

Formula

C16H14O6
CAS No.
SMILES

O=C1C2=C(OC(C1)C3=CC=C(C(OC)=C3)O)C=C(O)C=C2O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(±)Homoeriodictyol Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)Homoeriodictyol69097-98-9Cytochrome P450CYPsaromataseCYP19human placental microsomesbreast cancerInhibitorinhibitorinhibit

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