2. Antibody-drug Conjugate/ADC Related
  3. ADC Payload
  4. INX-SM-6

INX-SM-6 can be used for targeted delivery of anti-inflammatory agent. INX-SM-6 inhibits LPS-induced IL-1β production in human PBMCS.

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INX-SM-6

INX-SM-6 화학구조

CAS No. : 2734878-16-9

사이즈 가격 재고 수량
1 mg 해외재고보유
5 mg 해외재고보유
10 mg   견적 받기  
50 mg   견적 받기  

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

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INX-SM-6 Related Antibodies

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  • 순도&문서

  • References

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제품 설명

INX-SM-6 can be used for targeted delivery of anti-inflammatory agent. INX-SM-6 inhibits LPS-induced IL-1β production in human PBMCS[1].

분자량

576.70

화학식

C32H36N2O6S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([C@]([C@@]1([H])C[C@@]2([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(C=C4)C)([H])[C@H]5O)(O[C@@](C(S6)=CN=C6CC7=CC(N)=CC=C7)([H])O1)[C@]2(C5)C)CO
선적

Room temperature in continental US; may vary elsewhere.
보관

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

용액&용해도
In Vitro: 

DMSO : ≥ 50 mg/mL (86.70 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7340 mL 8.6700 mL 17.3400 mL
5 mM 0.3468 mL 1.7340 mL 3.4680 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
순도&문서

Purity: 98.85%

SDS (252 KB)

COA (251 KB) HNMR (255 KB) LCMS (94 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7340 mL 8.6700 mL 17.3400 mL 43.3501 mL
5 mM 0.3468 mL 1.7340 mL 3.4680 mL 8.6700 mL
10 mM 0.1734 mL 0.8670 mL 1.7340 mL 4.3350 mL
15 mM 0.1156 mL 0.5780 mL 1.1560 mL 2.8900 mL
20 mM 0.0867 mL 0.4335 mL 0.8670 mL 2.1675 mL
25 mM 0.0694 mL 0.3468 mL 0.6936 mL 1.7340 mL
30 mM 0.0578 mL 0.2890 mL 0.5780 mL 1.4450 mL
40 mM 0.0434 mL 0.2168 mL 0.4335 mL 1.0838 mL
50 mM 0.0347 mL 0.1734 mL 0.3468 mL 0.8670 mL
60 mM 0.0289 mL 0.1445 mL 0.2890 mL 0.7225 mL
80 mM 0.0217 mL 0.1084 mL 0.2168 mL 0.5419 mL
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INX-SM-6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

INX-SM-62734878-16-9ADC PayloadADC CytotoxinAnti-inflammationVISTAInhibitorinhibitorinhibit

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Inquiry Information

상품명:
INX-SM-6
Cat. No.:
HY-147119
수량:
MCE Japan Authorized Agent:

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SAFETY DATA SHEET (SDS)

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