L-656224
L-656224 is an orally active, potent and selective inhibitor of leukotriene biosynthesis in intact rat and human leukocytes and CXBG mastocytoma cells (IC50 values, 18-240 nM) and of human leukocyte and porcine leukocyte 5-lipoxygenase (IC50, 4 x 10-7 M). L-656224 is promising for research of asthma and peripheral analgesic agents.
For research use only. We do not sell to patients.
- CAS No.: 102612-16-8
- Formula: C20H21ClO3
- Molecular Weight:344.83
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
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CAS No. 102612-16-8
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Molecular Weight 344.83
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Formula C20H21ClO3
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SMILES
ClC1=CC(CCC)=C(C2=C1OC(CC3=CC=C(C=C3)OC)=C2C)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)