2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. J 104129 fumarate

J 104129 fumarate is a selective and orally active muscarinic M3 antagonist with Ki values of 4.2 nM and 490 nM for M3 and M2, respectively. J 104129 fumarate antagonized ACh-induced bronchoconstriction. J 104129 fumarate has the potential for the research of obstructive airway disease.

For research use only. We do not sell to patients.

J 104129 fumarate Chemical Structure

J 104129 fumarate Chemical Structure

CAS No. : 257603-40-0

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J 104129 fumarate Related Antibodies

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Description

J 104129 fumarate is a selective and orally active muscarinic M3 antagonist with Ki values of 4.2 nM and 490 nM for M3 and M2, respectively. J 104129 fumarate antagonized ACh-induced bronchoconstriction. J 104129 fumarate has the potential for the research of obstructive airway disease[1].

IC50 & Target[1]

mAChR3

4.2 nM (Ki)

mAChR2

490 nM (Ki)

Molecular Weight

500.63

Formula

C28H40N2O6
CAS No.
SMILES

O=C(NC1CCN(CC/C=C(C)/C)CC1)[C@@](O)(C2CCCC2)C3=CC=CC=C3.OC(/C=C/C(O)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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J 104129 fumarate Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

J 104129257603-40-0J104129J-104129mAChRMuscarinic acetylcholine receptorbronchoconstrictionobstructive airwayInhibitorinhibitorinhibit

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