CB-618
CB-618 is a β-lactamase inhibitor. CB-618 reversibly covalently inhibits Ambler class A, C, and some class D serine β-lactamases. CB-618 has weak antibacterial activity as a single agent, but it significantly enhances the antibacterial activity of Meropenem (HY-13678) against enzyme-producing Enterobacteriaceae. CB-618 can be used in research on drug-resistant bacteria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 1463520-70-8
- 分子式: C8H10N4O6S
- 分子量:290.25
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Beta-lactamase アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
化学情報
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CAS 番号 1463520-70-8
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分子量 290.25
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分子式 C8H10N4O6S
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SMILES
O=S(ON1[C@]2([H])CC[C@@H](C3=NN=CO3)[N@@](C2)C1=O)(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Papp-Wallace KM, Bonomo RA. New β-lactamase inhibitors in the clinic. Infectious disease clinics of North America. 2016 Jun;30(2):441. [Content Brief]
[2]. Griffith DC, et al. Pharmacokinetics/pharmacodynamics of vaborbactam, a novel beta-lactamase inhibitor, in combination with meropenem. Antimicrobial Agents and Chemotherapy. 2019 Jan;63(1):10-128. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
CB-618 関連分類
HY-120235 関連分類
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