Circulin B
Circulin B is a macrocyclic plant cyclopeptide. Circulin B functions as a plant defense peptide and exhibits antibacterial and anti-HIV activities. Circulin B has high binding affinity for the envelope protein of dengue virus, showing potential anti-dengue virus activity. Circulin B can be used in studies related to dengue virus infection, human immunodeficiency virus infection and microbial infection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 20905-50-4
- 分子式: C52H98N16O13
- 分子量:1155.43
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
199 μg/mL
Compound: Polymyxin E2-Ile
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Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
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[PMID: 29412662] |
体外実験
Circulin B exhibits non-allergenic and non-toxic properties in in silico profiling[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 20905-50-4
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分子量 1155.43
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分子式 C52H98N16O13
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SMILES
CC(C)CCCCC(N[C@@H](CCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCN)C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC1)=O)([H])[C@H](O)C)=O)CCN)=O)CCN)=O)([H])[C@@H](C)CC)=O)CC(C)C)=O)CCN)=O)=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Reena G, et al. In silico screening of plant peptides against the envelope protein of dengue virus. Trop Biomed. 2023;40(2):124-128. [Content Brief]
[2]. Balaraman S, et al. The structural and functional reliability of Circulins of Chassalia parvifolia for peptide therapeutic scaffolding. J Cell Biochem. 2018;119(5):3999-4008. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Circulin B 関連分類
HY-182588 関連分類
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Keywords
- Circulin B
- 20905-50-4
- Bacterial
- HIV
- Dengue Virus
- microbial infections
- dengue virus envelope protein
- fusion inhibition activity
- dengue virus infection
- human immunodeficiency virus infection
- human immunodeficiency virus
- *Chassalia parvifolia*
- intramolecular interactions
- plant defensive peptide
- antimicrobial activity
- Inhibitor
- inhibitor
- inhibit