Pdha1 - pyruvate dehydrogenase E1 subunit alpha 1 Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 29554

Summary

Enables pyruvate dehydrogenase (acetyl-transferring) activity. Involved in acetyl-CoA biosynthetic process from pyruvate. Located in mitochondrion. Part of pyruvate dehydrogenase complex. Used to study pyruvate decarboxylase deficiency. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human PDHA1 (pyruvate dehydrogenase E1 subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Pdha1 Products (1)

mRNA Protein Name
NM_001004072.2 NP_001004072.2 pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables pyruvate dehydrogenase (acetyl-transferring) activity IDA
IDA: Inferred from direct assay
7487891 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in acetyl-CoA biosynthetic process from pyruvate IDA
IDA: Inferred from direct assay
7487891 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
part of pyruvate dehydrogenase complex IDA
IDA: Inferred from direct assay
7487891 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

  • PDHE1-A type I

  • pyruvate dehydrogenase (lipoamide) alpha 1

  • pyruvate dehydrogenase E1 alpha 1 subunit

  • pyruvate dehydrogenase E1alpha subunit

  • pyruvate dehydrogenase alpha 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS24175 Pdha1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS10261 PDHA1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17710 Pdha1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Pdha1 NCBI NCBI:5160