Naxaprostene
Naxaprostene is a prostacyclin analogue. Naxaprostene was much more selective for IP receptors and tended towards partial agonism. Naxaprostene inhibits ADP-induced platelet aggregation. It has been shown to prevent rabbit carotid artery thrombosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 87269-59-8
- 分子式: C25H32O4
- 分子量:396.52
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
化学情報
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CAS 番号 87269-59-8
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分子量 396.52
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分子式 C25H32O4
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SMILES
O[C@@H](C1CCCCC1)/C=C/[C@@H]2[C@]3([H])[C@@](C[C@H]2O)([H])C/C(C3)=C\C4=CC(C(O)=O)=CC=C4
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別名
EL 784
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Maurin, N. Influence on platelet activity and red cell fluidity of epoprostenol and two stable prostacyclin analogues in vitro. Arzneimittelforschung 36(8), 1180-1183 (1986). [Content Brief]
[2]. Syed NI, Jones RL. Assessing the agonist profiles of the prostacyclin analogues treprostinil and naxaprostene, particularly their DP₁ activity. Prostaglandins Leukot Essent Fatty Acids. 2015 Apr;95:19-29. doi: 10.1016/j.plefa.2014.11.011. Epub 2014 Dec 5. PMID: 25542069. [Content Brief]
[3]. Schneider J. Antithrombotic effects of the prostacyclin analogue naxaprostene after oral and intraduodenal application in rabbit carotid artery thrombosis. Agents Actions Suppl. 1992;37:176-82. doi: 10.1007/978-3-0348-7262-1_24. PMID: 1632291. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Naxaprostene 関連分類
HY-165434 関連分類
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