Sodium mercaptopyruvate
Based on 1 Customer Validation
Sodium mercaptopyruvate serves as a substrate for Lactate dehydrogenase and Sulfurtransferase. Sodium mercaptopyruvate forms through enzymatic transamination and oxidative deamination of L-cysteine (HY-Y0337). Sodium mercaptopyruvate abolishes lactate dehydrogenase reaction activity. It increases urinary thiosulfate excretion, fails to sustain rat growth by replacing L-cystine (HY-N0394), and does not induce morbidity or mortality in mice. Sodium mercaptopyruvate is applicable to research related to 3-mercaptopyruvate disulfiduria and 3-mercaptolactate disulfiduria.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 10255-67-1
- 分子式: C3H3NaO3S
- 分子量:142.11
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保管条件:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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生物活性
Sodium mercaptopyruvate serves as an excellent substrate for bovine heart lactate dehydrogenase, and supports rapid stoichiometric NADH oxidation within 5 min[1].
Sodium mercaptopyruvate (5-10 mM; up to 4 h) loses lactate dehydrogenase reaction activity over time under neutral pH conditions: at pH 7.0 and 25°C, 50% of its activity is lost at approximately 80 minutes, and its stability increases at lower pH values[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male mice (23-25 g body weight)[1]
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Dosage:7 μmol/g body weight; 100 mM (72-hour incubated form)
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Administration:Injection; single dose
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Result:Showed no morbidity or mortality in four mice over a 48-hour observation period.
Showed no morbidity or mortality in eight male mice over the observation period when injected with the 72-hour incubated 100 mM form.
化学情報
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CAS 番号 10255-67-1
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性状 Solid
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分子量 142.11
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分子式 C3H3NaO3S
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Color White to light yellow
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SMILES
O=C(C(CS)=O)O[Na]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
純度とドキュメンテーション
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データシート (270 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Sodium mercaptopyruvate 関連分類
HY-W170255 関連分類
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- Sodium mercaptopyruvate
- 10255-67-1
- Lactate Dehydrogenase
- Drug Derivative
- tRNA sulfurtransferase
- 3-mercaptopyruvate desulfurase
- rat
- 3-mercaptolactate disulfiduria
- 3-mercaptopyruvate disulfiduria
- L-cysteine
- mice
- lactate dehydrogenase
- glutamine transaminase
- 3-mercaptopyruvate sulfurtransferase
- Inhibitor
- inhibitor
- inhibit