Vinorelbine tartrate solution
Vinorelbine tartrate solution is mainly composed of Vinorelbine ditartrate (HY-12053A). Vinorelbine (ditartrate) is an anti-mitotic agent which inhibits the proliferation of Hela cells with IC50 of 1.25 nM.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 125317-39-7
- 分子式: C53H66N4O20
- 分子量:1079.11
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
化学情報
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CAS 番号 125317-39-7
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分子量 1079.11
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分子式 C53H66N4O20
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SMILES
CC[C@@]12C=CCN3CC[C@](C4=C(N5C)C=C(OC)C([C@@](CC6([H])C=C(CN(C7)C6)CC)(C(OC)=O)C8=C7C9=C(N8)C=CC=C9)=C4)([C@@]5([C@](O)([C@@H]2OC(C)=O)C(OC)=O)[H])[C@]13[H].O=C([C@@H]([C@H](C(O)=O)O)O)O.O=C([C@@H]([C@H](C(O)=O)O)O)O
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別名
KW-2307 solution; Nor-5'-anhydrovinblastine ditartrate solution
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Ngan VK, et al. Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine. Mol Pharmacol. 2001 Jul;60(1):225-32. [Content Brief]
[2]. Liu XM, et al. Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen-independent prostate cancer cells. Br J Cancer. 2003 Oct 20;89(8):1566-73. [Content Brief]
[3]. Poirier VJ, et al. Toxicity, dosage, and efficacy of vinorelbine (Navelbine) in dogs with spontaneous neoplasia. J Vet Intern Med. 2004 Jul-Aug;18(4):536-9. [Content Brief]
[4]. Pierro JA, et al. Phase I clinical trial of vinorelbine in tumor-bearing cats. J Vet Intern Med. 2013 Jul-Aug;27(4):943-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)