Antitumor agent-173
Antitumor agent-173 (Compound 4b) is a prodrug of Cycloicaritin (HY-N1940). Antitumor agent-173 is a substrate for OATP2B1. Antitumor agent-173 selectively inhibits the growth of tumor Antitumor agent-173 significantly increases the oral bioavailability of Cycloicaritin and exerts good antitumor activity and safety.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C28H31NO9
- 분자량:525.55
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| NIH3T3 | IC50 |
>100 μM
Compound: 4b
|
Cytotoxicity against mouse 3T3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against mouse 3T3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 38972080] |
Chemical Information
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분자량 525.55
-
화학식 C28H31NO9
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SMILES
COC(C=C1)=CC=C1C2=C(OC(N[C@@H](CC(C)C)C(O)=O)=O)C(C3=C(O)C=C4C(CCC(C)(C)O4)=C3O2)=O
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)