D-Sorbitol-13C
Based on 1 Customer Validation
D-Sorbitol-13C is the 13C labeled D-Sorbitol. D-Sorbitol (Sorbitol) is a six-carbon sugar alcohol and can used as a sugar substitute. D-Sorbitol can be used as a stabilizing excipient and/or isotonicity agent, sweetener, humectant, thickener and dietary s
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 98.0%
- CAS No.: 287100-73-6
- 화학식: C513CH14O6
- 분자량:183.16
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 287100-73-6
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Unlabeled Cas 50-70-4
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Appearance Solid
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분자량 183.16
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화학식 C513CH14O6
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Color White to off-white
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SMILES
OC[13C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
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Synonyms
Sorbitol-13C; D-Glucitol-13C
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
H2O : 250 mg/mL (1364.93 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Ranjeet Prasad Dash, et al. Use of sorbitol as pharmaceutical excipient in the present day formulations - issues and challenges for drug absorption and bioavailability. Drug Dev Ind Pharm. 2019 Sep;45(9):1421-1429. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.4597 mL | 27.2985 mL | 54.5971 mL | 136.4927 mL |
| 5 mM | 1.0919 mL | 5.4597 mL | 10.9194 mL | 27.2985 mL | |
| 10 mM | 0.5460 mL | 2.7299 mL | 5.4597 mL | 13.6493 mL | |
| 15 mM | 0.3640 mL | 1.8199 mL | 3.6398 mL | 9.0995 mL | |
| 20 mM | 0.2730 mL | 1.3649 mL | 2.7299 mL | 6.8246 mL | |
| 25 mM | 0.2184 mL | 1.0919 mL | 2.1839 mL | 5.4597 mL | |
| 30 mM | 0.1820 mL | 0.9100 mL | 1.8199 mL | 4.5498 mL | |
| 40 mM | 0.1365 mL | 0.6825 mL | 1.3649 mL | 3.4123 mL | |
| 50 mM | 0.1092 mL | 0.5460 mL | 1.0919 mL | 2.7299 mL | |
| 60 mM | 0.0910 mL | 0.4550 mL | 0.9100 mL | 2.2749 mL | |
| 80 mM | 0.0682 mL | 0.3412 mL | 0.6825 mL | 1.7062 mL | |
| 100 mM | 0.0546 mL | 0.2730 mL | 0.5460 mL | 1.3649 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Sorbitol-13C Related Classifications
HY-B0400S1 Related Classifications
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