Dexamethasone acetate (Standard)
Based on 1 Customer Validation
Dexamethasone acetate (Standard) (Dexamethasone 21-acetate (Standard)) is the analytical standard of Dexamethasone acetate (HY-14648A). This product is intended for research and analytical applications. Dexamethasone acetate (Dexamethasone 21-acetate) is the acetate form of the glucocorticoid Dexamethasone (HY-14648). Dexamethasone acetate has a longer duration of action than Dexamethasone. Dexamethasone acetate can accumulate at inflammatory sites, in mouse liver and mouse lung via nanostructured lipid carriers. Dexamethasone acetate can be used to prepare topical formulations for studies related to sensorineural hearing loss, γ-carrageenan-induced paw edema, chronic active hepatitis, pulmonary diseases, and inflammation after vitreoretinal surgery.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98.93%
- CAS No.: 1177-87-3
- 화학식: C24H31FO6
- 분자량:434.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- 순도&문서
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Help & FAQs
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HY-14648A
Dexamethasone acetateCorticosteroid Ester -
HY-B1618
CorticosteroneEndogenous Glucocorticoids -
HY-13683
MifepristoneProgesterone Receptor Antagonist -
HY-N0583
HydrocortisoneGlucocorticoid Receptor Agonist -
HY-14648
DexamethasoneGR Agonist -
HY-B0260
MethylprednisoloneGlucocorticoid -
HY-14648C
Dexamethasone (Water Soluble)Muscular Atrophy/Hypertension/Depression Modeling Reagent -
HY-17463
PrednisoloneGlucocorticoid -
HY-N0583R
Hydrocortisone (Standard) -
HY-14648R
Dexamethasone (Standard) -
HY-13580
BudesonideGlucocorticoid Receptor Agonist -
HY-B1618R
Corticosterone (Standard)
Product Information
Information
신청
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 1177-87-3
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Appearance Solid
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분자량 434.50
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화학식 C24H31FO6
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Color White to off-white
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SMILES
C[C@@]1([C@@]2(O)C(COC(C)=O)=O)[C@](C[C@H]2C)([H])[C@@](CCC3=CC4=O)([H])[C@@](F)([C@]3(C=C4)C)[C@@H](O)C1
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Synonyms
Dexamethasone 21-acetate (Standard); Hexadecadrol acetate (Standard)
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Handling Instructions (2659 KB)
References
[1]. LaLone CA, et al. Effects of a glucocorticoid receptor agonist, Dexamethasone, on fathead minnow reproduction, growth, and development. Environ Toxicol Chem. 2012 Mar;31(3):611-22. [Content Brief]
[2]. Adcock IM, et al. Ligand-induced differentiation of glucocorticoid receptor (GR) trans-repression and transactivation: preferential targetting of NF-kappaB and lack of I-kappaB involvement. Br J Pharmacol. 1999 Jun;127(4):1003-11 [Content Brief]
[3]. Rocksén D, et al. Differential anti-inflammatory and anti-oxidative effects of Dexamethasone and N-acetylcysteine in endotoxin-induced lung inflammation. Clin Exp Immunol. 2000 Nov;122(2):249-56 [Content Brief]
[4]. Roussel D, et al. Dexamethasone treatment specifically increases the basal proton conductance of rat liver mitochondria. FEBS Lett. 2003 Apr 24;541(1-3):75-9. [Content Brief]
[5]. Ballabh P, et al. Neutrophil and monocyte adhesion molecules in bronchopulmonary dysplasia, and effects of corticosteroids. Arch Dis Child Fetal Neonatal Ed. 2004 Jan;89(1):F76-83. [Content Brief]
[6]. Heidi Ledford. et al. Coronavirus Breakthrough: Dexamethasone Is First Drug Shown to Save Lives. Nature. 2020 Jun 16. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Dexamethasone acetate (Standard) Related Classifications
HY-14648AR Related Classifications
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