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KRAS-IN-5

KRAS-IN-5 (Compound Ex 6) is an orally active and selective inhibitor targeting KRAS mutants (including KRASG12D, KRASG12V, KRASWT) with a GNE IC50 value of 1.3 nM against KRASG12D. KRAS-IN-5 blocks tumor cell proliferation by inhibiting KRAS-mediated signaling pathways (e.g., reducing ERK phosphorylation). KRAS-IN-5 is promising for research of KRAS mutation-related cancers, such as pancreatic cancer, colorectal cancer, lung cancer.

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  • CAS No.: 3082412-00-5
  • 화학식: C35H36F3N7O3
  • 분자량:659.70
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • KRAS-IN-5 Chemical Structure
    KRAS-IN-5 Chemical Structure
CAS No.: 3082412-00-5
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  • KRAS-IN-5 Chemical Structure
    KRAS-IN-5 Chemical Structure
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  • KRAS-IN-5