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Cat. No.: HY-161751

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MJ34

MJ34 is a potent inhibitor of GSK-3β and GSK-3α, with the IC₅₀s of 15.4 nM and 31.5 nM, respectively. MJ34 plays an important role in cancer research

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CAS No.: 2099015-13-9
화학식: C₁₉H₁₇N₅
분자량:315.37

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

MJ34 Chemical Structure

CAS No.: 2099015-13-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

MJ34 is a potent inhibitor of GSK-3β and GSK-3α, with the IC₅₀s of 15.4 nM and 31.5 nM, respectively. MJ34 plays an important role in cancer research^[1]

IC₅₀ & Target

GSK-3β

15.4 nM (IC₅₀)

GSK-3α

31.5 nM (IC₅₀)

All GSK-3 Isoforms :

Chemical Information

CAS No. 2099015-13-9
분자량 315.37
화학식 C₁₉H₁₇N₅
SMILES

NC1=NC=CC(C2=CNC3=NC=C(C=C32)C4=C(CC)C=CC=C4)=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mir Owais Ayaz, et al. Identification of a novel GSK3β inhibitor involved in abrogating KRas dependent pancreatic tumors in Wnt/beta-catenin and NF-kB dependent manner. Life Sci. 2024 Aug 15:351:122840. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=

Concentration Concentration

×

Volume Volume

×

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

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Volume _(start) Volume _(start)

=

Concentration _(final) Concentration _(final)

×

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
Chemical Information
순도&문서
References