TEAD-IN-19
TEAD-IN-19 (Compound 1l) is a transcriptional inhibitor of TEAD, exhibiting inhibition rates of 38.5%, 36.2%, 57.8%, and 71.3% against TEAD1, TEAD2, TEAD3, and TEAD4, respectively, at a concentration of 10 μM. TEAD-IN-19 shows potent anti-proliferative and anti-migratory activities in prostate cancer cell lines and significantly reduces the expression of TEAD-regulated downstream genes. TEAD-IN-19 holds promise for research in the field of cancer therapy.
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- 화학식: C33H19ClN2O2
- 분자량:510.97
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
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Biological Activity
Chemical Information
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분자량 510.97
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화학식 C33H19ClN2O2
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SMILES
CN(C1=CC=CC=C1C(O)=O)C(C=C2)=CC=C2NC(C=C3)=C(Cl)C=C3C4567C89%10C%11%12(C%10%136(C)C%14%15%167)C%17%13%16C%11%18%19C%128%20C49%21C%22%155C%18%17%14C%19%20%21%22
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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