Uric acid-15N2
Based on 1 publication(s) in Google Scholar
Uric acid-15N2 is the 15N-labeled Uric acid (HY-B2130). Uric acid is an orally active oxygen free radical scavenger that helps maintain stable blood pressure and combat oxidative stress. Uric acid can scavenge ROS, such as singlet oxygen and peroxynitrite, and inhibit lipid peroxidation. Uric acid can be used as a modeling agent in research on hyperuricemia-induced hypertension models.
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- Purity : 99.95%
- CAS No.: 62948-75-8
- 화학식: C5H4N215N2O3
- 분자량:170.10
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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HY-B2130
Uric acidOxygen Radical Scavenger -
HY-Y0252S1
L-Proline-d3Stable Isotope -
HY-N0091S5
Hypoxanthine-d4Stable Isotope -
HY-B2130R
Uric acid (Standard)Reference Standard -
HY-W017389S
Xanthine-13C,15N2Stable Isotope -
HY-N0658S6
L-Threonine-13C4Stable Isotope -
HY-Y0271S1
Urea-d4Stable Isotope -
HY-Y0252S
L-Proline-13C5Stable Isotope -
HY-N0394S1
L-Cystine-d4Stable Isotope -
HY-W008638
2'-DeoxyinosineProduct of 2'-Deoxyadenosine -
HY-N0543S
Allantoin-13C2,15N4Stable Isotope -
HY-113378S
3-Hydroxybutyric acid-d4 sodiumStable Isotope
Publications Citing Use of MedChemExpress (MCE) Uric acid-15N2
MoreAll Endogenous Metabolite Isoforms
More
Biological Activity
제품 설명
IC50 & Target
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Human Endogenous Metabolite |
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
신청
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 62948-75-8
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Unlabeled CAS 69-93-2
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Appearance Solid
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분자량 170.10
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화학식 C5H4N215N2O3
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Color White to off-white
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SMILES
O=C1C2=C([15NH]C([15NH]1)=O)NC(N2)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
용액&용해도
In Vitro:
H2O : 5.88 mg/mL (34.57 mM; ultrasonic and adjust pH to 10 with 1M NaOH)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (286 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 2020;50(4):359-375. [Content Brief]
[2]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.8789 mL | 29.3945 mL | 58.7889 mL | 146.9724 mL |
| 5 mM | 1.1758 mL | 5.8789 mL | 11.7578 mL | 29.3945 mL | |
| 10 mM | 0.5879 mL | 2.9394 mL | 5.8789 mL | 14.6972 mL | |
| 15 mM | 0.3919 mL | 1.9596 mL | 3.9193 mL | 9.7982 mL | |
| 20 mM | 0.2939 mL | 1.4697 mL | 2.9394 mL | 7.3486 mL | |
| 25 mM | 0.2352 mL | 1.1758 mL | 2.3516 mL | 5.8789 mL | |
| 30 mM | 0.1960 mL | 0.9798 mL | 1.9596 mL | 4.8991 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Uric acid-15N2 Related Classifications
HY-B2130S1 Related Classifications
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