1. GPCR/G Protein MAPK/ERK Pathway
  2. Ras
  3. Glecirasib

Glecirasib  (Synonyms: JAB-21822; KRAS G12C inhibitor 36)

Cat. No.: HY-143589
Handling Instructions

Glecirasib (KRAS G12C inhibitor 36) is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. Glecirasib has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021121367A1, compound 1-2).

For research use only. We do not sell to patients.

Glecirasib Chemical Structure

Glecirasib Chemical Structure

CAS No. : 2657613-87-9

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Description

Glecirasib (KRAS G12C inhibitor 36) is a potent inhibitor of KRAS G12C. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. Glecirasib has the potential for the research of KRAS G12C-mediated cancer (extracted from patent WO2021121367A1, compound 1-2)[1].

Molecular Weight

640.03

Formula

C31H26ClF4N7O2

CAS No.
SMILES

N#CC1=C(N2CCN(CC2)C(C=C)=O)C3=C(N=C(C4=C(N)C(F)=C(F)C(F)=C4F)C(Cl)=C3)N(C5=C(C)C=CN=C5C(C)C)C1=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Glecirasib Related Classifications

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The dilution calculator equation

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Glecirasib
Cat. No.:
HY-143589
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