L-β-Imidazolelactic acid
Based on 1 Customer Validation
L-β-Imidazolelactic acid is an inhibitor of Cholinesterase and Monoamine oxidase, and also the final metabolite of L-Histidine (HY-N0832). L-β-Imidazolelactic acid increases the activity of Superoxide dismutase. L-β-Imidazolelactic acid is applicable to research related to liver cirrhosis and histidinemia.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 14403-45-3
- Formula: C6H8N2O3
- Molecular Weight:156.14
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
L-β-Imidazolelactic acid (0.1-10 mM; 1 h for oxidative stress measurements; 1-10 mM for enzyme assays) exhibits concentration-dependent effects in ex vivo cerebral cortex homogenates from 30-day-old Wistar rats: it stimulates oxidative stress (increased chemiluminescence) at 0.5 and 1 mM, exerts antioxidant effects (decreased chemiluminescence, decreased TBA-RS, increased SOD activity) at 5 and 10 mM, and does not alter TRAP, CAT, or GSH-Px activity at any tested concentration[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 14403-45-3
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Appearance Solid
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Molecular Weight 156.14
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Formula C6H8N2O3
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Color White to off-white
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SMILES
C(C1=CN=CN1)[C@@H](C(=O)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 5 mg/mL (32.02 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[2]. Tansini CM, et al. Effects of histidine and imidazolelactic acid on various parameters of the oxidative stress in cerebral cortex of young rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2004 Apr;22(2):67-72. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.4045 mL | 32.0225 mL | 64.0451 mL | 160.1127 mL |
| 5 mM | 1.2809 mL | 6.4045 mL | 12.8090 mL | 32.0225 mL | |
| 10 mM | 0.6405 mL | 3.2023 mL | 6.4045 mL | 16.0113 mL | |
| 15 mM | 0.4270 mL | 2.1348 mL | 4.2697 mL | 10.6742 mL | |
| 20 mM | 0.3202 mL | 1.6011 mL | 3.2023 mL | 8.0056 mL | |
| 25 mM | 0.2562 mL | 1.2809 mL | 2.5618 mL | 6.4045 mL | |
| 30 mM | 0.2135 mL | 1.0674 mL | 2.1348 mL | 5.3371 mL |
L-β-Imidazolelactic acid Related Classifications
HY-W203728 Related Classifications
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