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Cat. No.: HY-170407

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mTOR/GSPT1 ligand-1

mTOR/GSPT1 ligand-1 is a mTOR/GSPT1 ligand, which can be used for the synthesis of PROTACs, such as YB-3-17 (HY-170405).

For research use only. We do not sell to patients.

CAS No.: 2250062-05-4
Formula: C₁₇H₁₈N₈O
Molecular Weight:350.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

mTOR/GSPT1 ligand-1 Chemical Structure

CAS No.: 2250062-05-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

mTOR/GSPT1 ligand-1 is a mTOR/GSPT1 ligand, which can be used for the synthesis of PROTACs, such as YB-3-17 (HY-170405)^[1].

IC₅₀ & Target

GSPT1

All mTOR Isoforms :

Chemical Information

CAS No. 2250062-05-4
Molecular Weight 350.38
Formula C₁₇H₁₈N₈O
SMILES

NC1=NC2=C(C=CC(C3=NN(C4=NC=NC(N)=C43)C5CCNCC5)=C2)O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Liu Y, et al., A Dual-Target and Dual-Mechanism Design Strategy by Combining Inhibition and Degradation Together. J Am Chem Soc. 2024 Dec 2. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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mTOR/GSPT1 ligand-1

All mTOR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

mTOR/GSPT1 ligand-1 Related Classifications

HY-170407 Related Classifications