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Multi-target kinase-IN-5

Multi-target kinase-IN-5 (Compound 23) is an orally active ERK1/2 inhibitor (IC50 values are 3.04 nM and 1.57 nM, respectively). Multi-target kinase-IN-5 significantly inhibits cancer cell proliferation, migration and invasion, and induces cell apoptosis and cell cycle arrest. Multi-target kinase-IN-5 inhibits the phosphorylation of ERK1/2 and downregulates the activity of its downstream substrate RSK to exert anti-tumor effects. Multi-target kinase-IN-5 can be used in cancer research.

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  • 화학식: C20H18ClFN4O3
  • 분자량:416.83
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Multi-target kinase-IN-5 Chemical Structure
    Multi-target kinase-IN-5 Chemical Structure
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  • Multi-target kinase-IN-5 Chemical Structure
    Multi-target kinase-IN-5 Chemical Structure
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  • Multi-target kinase-IN-5