2. Metabolic Enzyme/Protease
  3. NADPH Oxidase
  4. NOX2-IN-2

NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells.

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NOX2-IN-2

NOX2-IN-2 Estructura química

No. CAS : 2648709-79-7

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NOX2-IN-2 Related Antibodies

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NOX1 NOX2 NOX4 NOX5 DUOX1

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Descripciòn

NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells[1].

Peso molecular

471.51

Fòrmula

C25H25N7O3
No. CAS
SMILES

NC1=NC2=CC=C(C=C2C=C1)OCC3=CN(N=N3)CCOCCOC4=CC=C5N=C(C=CC5=C4)N
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Room temperature in continental US; may vary elsewhere.
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NOX2-IN-2 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NOX2-IN-22648709-79-7NADPH OxidaseNOXNOX2p47phox-p22phoxprotein-protein interactionROSInhibitorinhibitorinhibit

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Nombre del producto:
NOX2-IN-2
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HY-156425
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