P2Y2R/GPR17 antagonist 1
Based on 1 Customer Validation
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R and GPR17 antagonist with IC50 values of 3.17 µM and 1.67 µM against P2Y2R and GPR17, respectively. P2Y2R/GPR17 antagonist 1 shows excellent metabolic stability in human liver microsomes.
For research use only. We do not sell to patients.
- Purity: 98.09%
- CAS No.: 2395016-49-4
- Formula: C19H13ClN2O6S
- Molecular Weight:432.83
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
IC50: 1.67 µM (GPR17), 3.17 µM (P2Y2R)[1]
Chemical Information
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CAS No. 2395016-49-4
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Appearance Solid
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Molecular Weight 432.83
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Formula C19H13ClN2O6S
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Color Light yellow to yellow
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SMILES
O=C(C1=C(C=CC=C1)Cl)NC2=CC=C(C=C2)S(=O)(OC3=CC([N+]([O-])=O)=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (288.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.3104 mL | 11.5519 mL | 23.1038 mL | 57.7594 mL |
| 5 mM | 0.4621 mL | 2.3104 mL | 4.6208 mL | 11.5519 mL | |
| 10 mM | 0.2310 mL | 1.1552 mL | 2.3104 mL | 5.7759 mL | |
| 15 mM | 0.1540 mL | 0.7701 mL | 1.5403 mL | 3.8506 mL | |
| 20 mM | 0.1155 mL | 0.5776 mL | 1.1552 mL | 2.8880 mL | |
| 25 mM | 0.0924 mL | 0.4621 mL | 0.9242 mL | 2.3104 mL | |
| 30 mM | 0.0770 mL | 0.3851 mL | 0.7701 mL | 1.9253 mL | |
| 40 mM | 0.0578 mL | 0.2888 mL | 0.5776 mL | 1.4440 mL | |
| 50 mM | 0.0462 mL | 0.2310 mL | 0.4621 mL | 1.1552 mL | |
| 60 mM | 0.0385 mL | 0.1925 mL | 0.3851 mL | 0.9627 mL | |
| 80 mM | 0.0289 mL | 0.1444 mL | 0.2888 mL | 0.7220 mL | |
| 100 mM | 0.0231 mL | 0.1155 mL | 0.2310 mL | 0.5776 mL |
P2Y2R/GPR17 antagonist 1 Related Classifications
HY-146486 Related Classifications
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