Poly-L-ornithine hydrobromide (MW 5000-15000)
Based on 1 Customer Validation
Poly-L-ornithine (hydrobromide) (MW 5000-15000) (L-Ornithine homopolymer (hydrobromide) (MW 5000-15000)) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- CAS No.: 27378-49-0
- Formula: (C5H12N2O2)n.xHBr
- Molecular Weight:5000-15000
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
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Cell Line:human umbilical vein endothelial cells (HUVECs)
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Concentration:A/N ratio = 1.75
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Incubation Time:24 h
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Result:Exhibited a significantly lower colocalization ratio (~27%) of mRNA with late endolysosomes compared to parent BP-PLO (~65%) and TP-nCCP/PLO (~89%).
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Animal Model:C57BL/6J (8-week-old male, 20-25 g, lysolecithin-induced spinal cord focal demyelination)[2]
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Dosage:20 µg/mL; 100 µg/mL; 500 µg/mL
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Administration:intraspinal; co-injection with lysolecithin at time of injury
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Result:Promoted myelin regeneration and recovery of motor function at 100 μg/mL; and excessively high concentration (500 μg/mL) was actually harmful.
Chemical Information
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CAS No. 27378-49-0
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Appearance Solid
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Molecular Weight 5000-15000
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Formula (C5H12N2O2)n.xHBr
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Color White to off-white
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SMILES
CC([C@@H](N)CCCNC)=O.[n].[x].Br
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Synonyms
L-Ornithine homopolymer hydrobromide (MW 5000-15000)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)