PROTAC BRM/BRG1 degrader-2
PROTAC BRM/BRG1 degrader-2 (Example.004) is a PROTAC BRM/BRG1 degrader (DC50: < 10 nM in A549 cell; IC50: 15 nM for A549).
(Pink: SMARCA2/BRM/BAF190B/SNF2L2 and SMARCA4/BRG1/BAF190A ligand (HY-168248); Blue: VHL ligand (HY-112078); Black: linker (HY-168249)).
For research use only. We do not sell to patients.
- CAS No.: 2933124-32-2
- Formula: C50H60N12O5S
- Molecular Weight:941.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2933124-32-2
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Molecular Weight 941.15
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Formula C50H60N12O5S
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SMILES
NC(C1=C2C=C(C3=C(O)C=CC=C3)N=N1)=NN2C(CC4)CCN4C5=NC=C([C@H]6CC[C@H](C(N[C@@H](C(C)(C)C)C(N7C[C@H](O)C[C@H]7C(N[C@H](C8=CC=C(C9=C(C)N=CS9)C=C8)C)=O)=O)=O)CC6)C=N5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC BRM/BRG1 degrader-2 Related Classifications
HY-168247 Related Classifications
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